Advantages and disadvantages of cystatin С for assessment glomerular filtration rate

Abstract

Assessing the rate of glomerular filtration is important in the diagnosis and prognosis of complications of
kidney disease. Currently, creatinine is widely used in the assessment of glomerular filtration rate. However,
creatinine is an imperfect biomarker because the amount of creatinine in a deposit depends on a person’s age,
gender, race, muscle size, and some medications they are taking. With this in mind, it is important to find the
perfect biomarker and diagnose early kidney disease in determining and evaluating glomerular filtration rate.
There are now excellent biomarkers in measuring glomerular filtration rate that have the ability to detect,
predict, and diagnose disease at an early stage in a timely manner. One such biomarker is cystatin C. This article
describes the determination of glomerular filtration rate by cystatin C, its advantages and disadvantages, and
its application in clinical settings.
This article describes the determination of glomerular filtration rate by cystatin C, its advantages and
disadvantages, and its application in clinical settings.